Scrutinizing the drug resistance mechanism of multi- and extensively-drug resistant Mycobacterium tuberculosis: mutations versus efflux pumps

Scrutinizing the drug resistance mechanism of multi- and extensively-drug resistant Mycobacterium tuberculosis: mutations versus efflux pumps

Abstract Background In order to shorten the course of treatment and its effectiveness, it is essential to gain an in-depth insight into the drug resistance mechanisms of Mycobacterium tuberculosis (M. tuberculosis). Methods In this study, we evaluated the contribution of 26 drug efflux pumps plus ta...

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Bibliographic Details
Main Authors: Hasan Ghajavand, Mansour Kargarpour Kamakoli, Sharareh Khanipour, Shahin Pourazar Dizaji, Morteza Masoumi, Fatemeh Rahimi Jamnani, Abolfazl Fateh, Mehdi Yaseri, Seyed Davar Siadat, Farzam Vaziri
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Tuberculosis
VP
Efflux pumps
MDR
Pre-XDR
XDR
Online Access:http://link.springer.com/article/10.1186/s13756-019-0516-4

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