Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.

Sorting nexin 5 (Snx5) has been posited to regulate the degradation of epidermal growth factor receptor and the retrograde trafficking of cation-independent mannose 6-phosphate receptor/insulin-like growth factor II receptor. Snx5 has also been suggested to interact with Mind bomb-1, an E3 ubiquitin...

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Bibliographic Details
Main Authors: Sun-Kyoung Im, HyoBin Jeong, Hyun-Woo Jeong, Kyong-Tai Kim, Daehee Hwang, Machiko Ikegami, Young-Yun Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602295?pdf=render

Internet

http://europepmc.org/articles/PMC3602295?pdf=render

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