Developmental Easing of Short-Term Depression in “Winner” Climbing Fibers

Developmental Easing of Short-Term Depression in “Winner” Climbing Fibers

The postnatal development of cerebellar climbing fiber (CF) to Purkinje neuron (PN) synapses is characterized by a substantial pruning during the first 3 weeks after birth, switching from multiple- to single-CF innervation. Previous studies suggested that CF maturation is governed by bidirectional c...

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Bibliographic Details
Main Authors: Christina Pätz, Simone Brachtendorf, Jens Eilers
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebellum
climbing fibers
Purkinje neuron
short-term plasticity
paired-pulse depression
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00183/full

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