Anticancer Activity of Gukulenin A Isolated from the Marine Sponge <i>Phorbas gukhulensis</i> In Vitro and In Vivo

Anticancer Activity of Gukulenin A Isolated from the Marine Sponge <i>Phorbas gukhulensis</i> In Vitro and In Vivo

Gukulenin A is a bis-tropolone tetraterpenoid isolated from the marine sponge <i>Phorbas gukhulensis</i>. In this study, we examined the anticancer activities of gukulenin A in ovarian cancer cell lines (A2780, SKOV3, OVCAR-3, and TOV-21G) and in an ovarian cancer mouse model generated b...

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Bibliographic Details
Main Authors: Ji-Hye Ahn, Jeong-Hwa Woo, Jung-Rae Rho, Jung-Hye Choi
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Marine Drugs
Subjects:
gukulenin A
<i>Phorbas gukhulensis</i>
ovarian cancer
apoptosis
tumor xenograft model
Online Access:https://www.mdpi.com/1660-3397/17/2/126

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