Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition?

Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition?

Recent research has linked sphingolipid (SL) metabolism with cystic fibrosis transmembrane conductance regulator (CFTR) activity, affecting bioactive lipid mediator sphingosine-1-phosphate (S1P). We hypothesize that loss of CFTR function in cystic fibrosis (CF) patients influenced plasma S1P levels....

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Bibliographic Details
Main Authors: Emina Halilbasic, Elisabeth Fuerst, Denise Heiden, Lukasz Japtok, Susanne C. Diesner, Michael Trauner, Askin Kulu, Peter Jaksch, Konrad Hoetzenecker, Burkhard Kleuser, Lili Kazemi-Shirazi, Eva Untersmayr
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nutrients
Subjects:
sphingolipids
sphingosine-1-phosphate
intestine
high density lipoproteins
cystic fibrosis
δf508 mutation
immunonutrition
Online Access:https://www.mdpi.com/2072-6643/12/3/765

Internet

https://www.mdpi.com/2072-6643/12/3/765

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