Iron Limitation in Klebsiella pneumoniae Defines New Roles for Lon Protease in Homeostasis and Degradation by Quantitative Proteomics
Nutrient adaptation is key in limiting environments for the promotion of microbial growth and survival. In microbial systems, iron is an essential component for many cellular processes, and bioavailability varies greatly among different conditions. In the bacterium, Klebsiella pneumoniae, the impact...
Main Authors: | Benjamin Muselius, Arjun Sukumaran, Jason Yeung, Jennifer Geddes-McAlister |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2020.00546/full |
Similar Items
-
Zinc limitation in Klebsiella pneumoniae profiled by quantitative proteomics influences transcriptional regulation and cation transporter-associated capsule production
by: A. Sukumaran, et al.
Published: (2021-02-01) -
The Mitochondrial Lon Protease: Novel Functions off the Beaten Track?
by: Wolfgang Voos, et al.
Published: (2020-02-01) -
Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
by: Istvan Botos, et al.
Published: (2019-11-01) -
The Glyoxysomal Protease LON2 Is Involved in Fruiting-Body Development, Ascosporogenesis and Stress Resistance in <i>Sordaria macrospora</i>
by: Antonia Werner, et al.
Published: (2021-01-01) -
Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging
by: Jenny K. Ngo, et al.
Published: (2013-01-01)