Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry

Domperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The m...

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Main Authors: P. Ravi Kumar, P. Bhanu Prakash, M. Murali Krishna, M. Santha Yadav, C. Asha Deepthi
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2006/640731
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spelling doaj-dd01fa086fb5455f876e86b729b3c8e72020-11-24T23:50:20ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102006-01-013314214510.1155/2006/640731Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV SpectrophotometryP. Ravi Kumar0P. Bhanu Prakash1M. Murali Krishna2M. Santha Yadav3C. Asha Deepthi4Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaDepartment of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaDomperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The methods involve solving of simultaneous equations and Q-value analysis based on measurement absorptivity at 216, 287 and 290 nm respectively. Linearity lies between 1-15 mcg/mL for domperidone and 0-50 mcg/mL for pantoprazole.http://dx.doi.org/10.1155/2006/640731
collection DOAJ
language English
format Article
sources DOAJ
author P. Ravi Kumar
P. Bhanu Prakash
M. Murali Krishna
M. Santha Yadav
C. Asha Deepthi
spellingShingle P. Ravi Kumar
P. Bhanu Prakash
M. Murali Krishna
M. Santha Yadav
C. Asha Deepthi
Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
E-Journal of Chemistry
author_facet P. Ravi Kumar
P. Bhanu Prakash
M. Murali Krishna
M. Santha Yadav
C. Asha Deepthi
author_sort P. Ravi Kumar
title Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
title_short Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
title_full Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
title_fullStr Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
title_full_unstemmed Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry
title_sort simultaneous estimation of domperidone and pantoprazole in solid dosage form by uv spectrophotometry
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2006-01-01
description Domperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The methods involve solving of simultaneous equations and Q-value analysis based on measurement absorptivity at 216, 287 and 290 nm respectively. Linearity lies between 1-15 mcg/mL for domperidone and 0-50 mcg/mL for pantoprazole.
url http://dx.doi.org/10.1155/2006/640731
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