Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry

Domperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The m...

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Bibliographic Details
Main Authors: P. Ravi Kumar, P. Bhanu Prakash, M. Murali Krishna, M. Santha Yadav, C. Asha Deepthi
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2006/640731
Description
Summary:Domperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The methods involve solving of simultaneous equations and Q-value analysis based on measurement absorptivity at 216, 287 and 290 nm respectively. Linearity lies between 1-15 mcg/mL for domperidone and 0-50 mcg/mL for pantoprazole.
ISSN:0973-4945
2090-9810