Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex

Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex

The antimicrobial activity of the chemokine CXCL10 against vegetative cells of Bacillus anthracis occurs via both bacterial FtsE/X-dependent and-independent pathways. Previous studies established that the FtsE/X-dependent pathway was mediated through interaction of the N-terminal region(s) of CXCL10...

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Bibliographic Details
Main Authors: Molly A. Hughes, Katie R. Margulieux, Benjamin K. Liebov, Venkata S. K. K. S. Tirumala, Arpita Singh, John H. Bushweller, Robert K. Nakamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Microbiology
Subjects:
Bacillus anthracis
chemokine
CXCL10
antimicrobial
FtsE/X
peptidoglycan
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00740/full

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