Cryopreserved Human Natural Killer Cells Exhibit Potent Antitumor Efficacy against Orthotopic Pancreatic Cancer through Efficient Tumor-Homing and Cytolytic Ability (Running Title: Cryopreserved NK Cells Exhibit Antitumor Effect)

Cryopreserved Human Natural Killer Cells Exhibit Potent Antitumor Efficacy against Orthotopic Pancreatic Cancer through Efficient Tumor-Homing and Cytolytic Ability (Running Title: Cryopreserved NK Cells Exhibit Antitumor Effect)

Pancreatic cancer is known to be highly aggressive, and desmoplasia-induced accumulation of extracellular matrix (ECM), which is a hallmark of many pancreatic cancers, severely restricts the therapeutic efficacy of both immunotherapeutics and conventional chemotherapeutics due to the ECM functioning...

Full description

Bibliographic Details
Main Authors: Eonju Oh, Bokyung Min, Yan Li, ChunYing Lian, JinWoo Hong, Gyeong-min Park, Bitna Yang, Sung Yoo Cho, Yu Kyeong Hwang, Chae-Ok Yun
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
adoptive cell therapy
allogeneic natural killer cells
cancer immunology
pancreatic cancer
apoptosis
Online Access:https://www.mdpi.com/2072-6694/11/7/966

Similar Items

Similar Items