Comparison of the curative effect and serum indexes of ultrasonic pneumatic and holmium laser technology for percutaneous nephrolithotomy treatment of complex renal calculus

• Main Authors: Cheng-Jun Qiu, Jin-Song Ao, Li Cheng, Bo Wang, Yu Zhou, Chang-Zhong Wang
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2017-06-01
• Series: Journal of Hainan Medical University
• Subjects: Complex renal calculus; Ultrasonic pneumatic; Holmium laser; Stress response; Inflammatory factors
• Online Access: http://www.hnykdxxb.com/PDF/201706/18.pdf

Objective: To study the differences in the curative effect and serum indexes of ultrasonic pneumatic and holmium laser technology for percutaneous nephrolithotomy treatment of complex renal calculus. Methods: A total of 78 patients with complex renal calculus who accepted surgical treatment in our hospital between May 2011 and January 2016 were collected, the operation methods and test results were reviewed, and then they were divided into the observation group (n=34) who accepted ultrasonic pneumatic treatment and the control group (n=44) who accepted holmium laser treatment. Ⅰstage stone clearance rate of two groups of patients were recorded; serum was collected, sarcosine oxidase method was used to detect serum renal function indexes, and ELISA method was used to detect the levels of inflammatory factors and stress hormones. Results: The mean lithotomy time of observation group was shorter than that of control group; differences in Ⅰstage stone clearance rate were not statistically significant between two groups of patients. 3 d after operation, serum renal function indexes Scr, BUN and CysC levels of observation group were lower than those of control group; serum inflammatory factors PCT, IL-1β, IL-22 and IL-13 levels of observation group were lower than those of control group while IL-4 level was higher than that of control group; serum stress hormones AngⅠ, AngⅡ, Adr and NE levels of observation group were lower than those of control group. Conclusion: Both ultrasonic pneumatic and holmium laser technology can effectively remove complex renal calculus and ultrasonic pneumatic technology has the advantages of quicker operation and less injury.