In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways
Abstract The ryanodine receptor 1 is a large calcium ion channel found in mammalian skeletal muscle. The ion channel gained a lot of attention recently, after multiple independent authors published near-atomic cryo electron microscopy data. Taking advantage of the unprecedented quality of structural...
Main Authors: | Leonard P. Heinz, Wojciech Kopec, Bert L. de Groot, Rainer H. A. Fink |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-25061-z |
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