Clinical Efficacy of Chelation Therapy in Patients with Low-Risk Myelodysplastic Syndrome
The present literature review provides evidence that in patients with low-risk myelodysplastic syndrome and transfusion dependence blood parameters and survival rates can be improved by administration of iron chelators. Dose adequacy and therapy duration underlie clinical efficacy of chelators. Toxi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Practical Medicine Publishing House
2019-03-01
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| Series: | Kliničeskaâ onkogematologiâ |
| Subjects: | |
| Online Access: |
http://bloodjournal.ru/wp-content/uploads/2019/03/2-6.pdf
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| Summary: | The present literature review provides evidence that in patients with low-risk myelodysplastic syndrome and transfusion dependence blood parameters and survival rates can be improved by administration of iron chelators. Dose adequacy and therapy duration underlie clinical efficacy of chelators. Toxicity can be reduced by administrating a new formula of deferasirox that does not need to be dissolved in liquid before consuming. |
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| ISSN: | 1997-6933 2500-2139 |