BRAF and beyond: Tailoring strategies for the individual melanoma patient

Until recently, options for therapy in metastatic melanoma were limited. The understanding of immune check-point blockade and the discovery of molecular pathways involving driver mutations like BRAF has transformed the therapeutic landscape in this disease. Ipilimumab was the first drug shown to imp...

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Bibliographic Details
Main Authors: Anthony Jarkowski, Nikhil I Khushalani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Carcinogenesis
Subjects:
MEK
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2014;volume=13;issue=1;spage=1;epage=1;aulast=Jarkowski