Structural and Kinetic Insights Into the Molecular Basis of Salt Tolerance of the Short-Chain Glucose-6-Phosphate Dehydrogenase From Haloferax volcanii

Structural and Kinetic Insights Into the Molecular Basis of Salt Tolerance of the Short-Chain Glucose-6-Phosphate Dehydrogenase From Haloferax volcanii

Halophilic enzymes need high salt concentrations for activity and stability and are considered a promising source for biotechnological applications. The model study for haloadaptation has been proteins from the Halobacteria class of Archaea, where common structural characteristics have been found. H...

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Bibliographic Details
Main Authors: Nicolás Fuentes-Ugarte, Sixto M. Herrera, Pablo Maturana, Victor Castro-Fernandez, Victoria Guixé
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Microbiology
Subjects:
short-chain dehydrogenase/reductase
glucose-6-phosphate dehydrogenase
archaea
haloadaptation
molecular dynamics simulations
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.730429/full

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