SARS-CoV-2 another kind of liver aggressor, how does it do that?

Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among pat...

Full description

Bibliographic Details
Main Authors: Sonia A. Lozano-Sepulveda, Kame Galan-Huerta, Natalia Martínez-Acuña, Daniel Arellanos-Soto, Ana María Rivas-Estilla
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268120301460
id doaj-dcb9942d870b4a8b87684da53aa32c89
record_format Article
spelling doaj-dcb9942d870b4a8b87684da53aa32c892021-06-09T05:57:11ZengElsevierAnnals of Hepatology1665-26812020-11-01196592596SARS-CoV-2 another kind of liver aggressor, how does it do that?Sonia A. Lozano-Sepulveda0Kame Galan-Huerta1Natalia Martínez-Acuña2Daniel Arellanos-Soto3Ana María Rivas-Estilla4Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoCorresponding author at: Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Ave. Francisco I. Madero y Ave. Gonzalitos s/n Col. Mitras Centro Monterrey, Nuevo León, 64460, Mexico.; Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoClinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients.http://www.sciencedirect.com/science/article/pii/S1665268120301460SARS-CoV-2LiverLiver impairmentCOVID-19ACE2
collection DOAJ
language English
format Article
sources DOAJ
author Sonia A. Lozano-Sepulveda
Kame Galan-Huerta
Natalia Martínez-Acuña
Daniel Arellanos-Soto
Ana María Rivas-Estilla
spellingShingle Sonia A. Lozano-Sepulveda
Kame Galan-Huerta
Natalia Martínez-Acuña
Daniel Arellanos-Soto
Ana María Rivas-Estilla
SARS-CoV-2 another kind of liver aggressor, how does it do that?
Annals of Hepatology
SARS-CoV-2
Liver
Liver impairment
COVID-19
ACE2
author_facet Sonia A. Lozano-Sepulveda
Kame Galan-Huerta
Natalia Martínez-Acuña
Daniel Arellanos-Soto
Ana María Rivas-Estilla
author_sort Sonia A. Lozano-Sepulveda
title SARS-CoV-2 another kind of liver aggressor, how does it do that?
title_short SARS-CoV-2 another kind of liver aggressor, how does it do that?
title_full SARS-CoV-2 another kind of liver aggressor, how does it do that?
title_fullStr SARS-CoV-2 another kind of liver aggressor, how does it do that?
title_full_unstemmed SARS-CoV-2 another kind of liver aggressor, how does it do that?
title_sort sars-cov-2 another kind of liver aggressor, how does it do that?
publisher Elsevier
series Annals of Hepatology
issn 1665-2681
publishDate 2020-11-01
description Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients.
topic SARS-CoV-2
Liver
Liver impairment
COVID-19
ACE2
url http://www.sciencedirect.com/science/article/pii/S1665268120301460
work_keys_str_mv AT soniaalozanosepulveda sarscov2anotherkindofliveraggressorhowdoesitdothat
AT kamegalanhuerta sarscov2anotherkindofliveraggressorhowdoesitdothat
AT nataliamartinezacuna sarscov2anotherkindofliveraggressorhowdoesitdothat
AT danielarellanossoto sarscov2anotherkindofliveraggressorhowdoesitdothat
AT anamariarivasestilla sarscov2anotherkindofliveraggressorhowdoesitdothat
_version_ 1721388514770157568