SARS-CoV-2 another kind of liver aggressor, how does it do that?
Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among pat...
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doaj-dcb9942d870b4a8b87684da53aa32c892021-06-09T05:57:11ZengElsevierAnnals of Hepatology1665-26812020-11-01196592596SARS-CoV-2 another kind of liver aggressor, how does it do that?Sonia A. Lozano-Sepulveda0Kame Galan-Huerta1Natalia Martínez-Acuña2Daniel Arellanos-Soto3Ana María Rivas-Estilla4Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoDepartment of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoCorresponding author at: Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Ave. Francisco I. Madero y Ave. Gonzalitos s/n Col. Mitras Centro Monterrey, Nuevo León, 64460, Mexico.; Department of Biochemistry and Molecular Medicine, School of Medicine and Hospital Universitario “Dr. Jose E. Gonzalez”, Autonomous University of Nuevo León, Monterrey, N.L, MexicoClinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients.http://www.sciencedirect.com/science/article/pii/S1665268120301460SARS-CoV-2LiverLiver impairmentCOVID-19ACE2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sonia A. Lozano-Sepulveda Kame Galan-Huerta Natalia Martínez-Acuña Daniel Arellanos-Soto Ana María Rivas-Estilla |
spellingShingle |
Sonia A. Lozano-Sepulveda Kame Galan-Huerta Natalia Martínez-Acuña Daniel Arellanos-Soto Ana María Rivas-Estilla SARS-CoV-2 another kind of liver aggressor, how does it do that? Annals of Hepatology SARS-CoV-2 Liver Liver impairment COVID-19 ACE2 |
author_facet |
Sonia A. Lozano-Sepulveda Kame Galan-Huerta Natalia Martínez-Acuña Daniel Arellanos-Soto Ana María Rivas-Estilla |
author_sort |
Sonia A. Lozano-Sepulveda |
title |
SARS-CoV-2 another kind of liver aggressor, how does it do that? |
title_short |
SARS-CoV-2 another kind of liver aggressor, how does it do that? |
title_full |
SARS-CoV-2 another kind of liver aggressor, how does it do that? |
title_fullStr |
SARS-CoV-2 another kind of liver aggressor, how does it do that? |
title_full_unstemmed |
SARS-CoV-2 another kind of liver aggressor, how does it do that? |
title_sort |
sars-cov-2 another kind of liver aggressor, how does it do that? |
publisher |
Elsevier |
series |
Annals of Hepatology |
issn |
1665-2681 |
publishDate |
2020-11-01 |
description |
Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients. |
topic |
SARS-CoV-2 Liver Liver impairment COVID-19 ACE2 |
url |
http://www.sciencedirect.com/science/article/pii/S1665268120301460 |
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