The insulin-like growth factor 2 gene in mammals: Organizational complexity within a conserved locus.
The secreted protein, insulin-like growth factor 2 (IGF2), plays a central role in fetal and prenatal growth and development, and is regulated at the genetic level by parental imprinting, being expressed predominantly from the paternally derived chromosome in mice and humans. Here, IGF2/Igf2 and its...
Main Authors: | Kabita Baral, Peter Rotwein |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0219155 |
Similar Items
-
Zmat2 in mammals: conservation and diversification among genes and Pseudogenes
by: Peter Rotwein, et al.
Published: (2020-01-01) -
Diversification of the insulin-like growth factor 1 gene in mammals.
by: Peter Rotwein
Published: (2017-01-01) -
in Humans and Other Primates: A Highly Conserved and Understudied Gene
by: Kabita Baral, et al.
Published: (2020-09-01) -
The Zmat2 gene in non-mammalian vertebrates: Organizational simplicity within a divergent locus in fish.
by: Peter Rotwein
Published: (2020-01-01) -
Biochemical characterization of diverse Stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-I gene transcription.
by: Ben Varco-Merth, et al.
Published: (2012-01-01)