Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst

Combining the Heck reaction with other transformations provides a powerful strategy to access diverse, complex compounds. Here, the authors report a weak coordination dominated Pd(0)-catalyzed quadruple C-H activation followed by hydro-functionalization, C-H silylation, and C-H borylation.

Bibliographic Details
Main Authors:	Bo-Cheng Tang, Wen-Xuan Lin, Xiang-Long Chen, Cai He, Jin-Tian Ma, Yan-Dong Wu, Yu Lan, An-Xin Wu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-19508-z

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spelling	doaj-dcb375263fd8416e8482f782663f053d2021-05-11T08:23:09ZengNature Publishing GroupNature Communications2041-17232020-11-0111111210.1038/s41467-020-19508-zQuadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalystBo-Cheng Tang0Wen-Xuan Lin1Xiang-Long Chen2Cai He3Jin-Tian Ma4Yan-Dong Wu5Yu Lan6An-Xin Wu7Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityCollege of Chemistry and Institute of Green Catalysis, Zhengzhou UniversityKey Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityKey Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityKey Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityKey Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityCollege of Chemistry and Institute of Green Catalysis, Zhengzhou UniversityKey Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal UniversityCombining the Heck reaction with other transformations provides a powerful strategy to access diverse, complex compounds. Here, the authors report a weak coordination dominated Pd(0)-catalyzed quadruple C-H activation followed by hydro-functionalization, C-H silylation, and C-H borylation.https://doi.org/10.1038/s41467-020-19508-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Bo-Cheng Tang Wen-Xuan Lin Xiang-Long Chen Cai He Jin-Tian Ma Yan-Dong Wu Yu Lan An-Xin Wu
spellingShingle	Bo-Cheng Tang Wen-Xuan Lin Xiang-Long Chen Cai He Jin-Tian Ma Yan-Dong Wu Yu Lan An-Xin Wu Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst Nature Communications
author_facet	Bo-Cheng Tang Wen-Xuan Lin Xiang-Long Chen Cai He Jin-Tian Ma Yan-Dong Wu Yu Lan An-Xin Wu
author_sort	Bo-Cheng Tang
title	Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst
title_short	Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst
title_full	Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst
title_fullStr	Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst
title_full_unstemmed	Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst
title_sort	quadruple c-h activation coupled to hydrofunctionalization and c-h silylation/borylation enabled by weakly coordinated palladium catalyst
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-11-01
description	Combining the Heck reaction with other transformations provides a powerful strategy to access diverse, complex compounds. Here, the authors report a weak coordination dominated Pd(0)-catalyzed quadruple C-H activation followed by hydro-functionalization, C-H silylation, and C-H borylation.
url	https://doi.org/10.1038/s41467-020-19508-z
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Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst

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