Genomic features of humoral immunity support tolerance model in Egyptian rousette bats

Genomic features of humoral immunity support tolerance model in Egyptian rousette bats

Summary: Bats asymptomatically harbor many viruses that can cause severe human diseases. The Egyptian rousette bat (ERB) is the only known reservoir for Marburgviruses and Sosuga virus, making it an exceptional animal model to study antiviral mechanisms in an asymptomatic host. With this goal in min...

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Bibliographic Details
Main Authors: Peter A. Larson, Maggie L. Bartlett, Karla Garcia, Joseph Chitty, Anne Balkema-Buschmann, Jonathan Towner, Jeffrey Kugelman, Gustavo Palacios, Mariano Sanchez-Lockhart
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
immunoglobulin heavy chain locus
Chiroptera
antiviral immunity
tolerance
Fc receptors
pentraxins
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004794

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