Correlation between dopamine receptor D2 expression and presence of abnormal involuntary movements in Wistar rats with hemiparkinsonism and dyskinesia

Correlation between dopamine receptor D2 expression and presence of abnormal involuntary movements in Wistar rats with hemiparkinsonism and dyskinesia

Parkinson's disease (PD) is characterised by motor alterations, which are commonly treated with l-DOPA. However, long-term l-DOPA use may cause dyskinesia. Although the pathogenic mechanism of l-DOPA-induced dyskinesia is unclear, the condition has been associated with alterations in dopamine r...

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Bibliographic Details
Main Authors: P.A. Caro Aponte, C.A. Otálora, J.C. Guzmán, L.F. Turner, J.P. Alcázar, E.L. Mayorga
Format: Article
Language:English
Published: Elsevier España 2021-04-01
Series:Neurología (English Edition)
Subjects:
Disquinesia
Enfermedad de Parkinson
l-DOPA
Movimientos involuntarios anormales
Ratas
Receptor dopaminérgico D2
Online Access:http://www.sciencedirect.com/science/article/pii/S2173580819301245

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http://www.sciencedirect.com/science/article/pii/S2173580819301245

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