Multidimensional heritability analysis of neuroanatomical shape

Neuroanatomical shape measurements are multidimensional geometric descriptions of brain structure. This study develops multivariate heritability analysis methods and examines structural brain MRI scans and genetic data to estimate the heritability of neuroanatomical shape.

Bibliographic Details
Main Authors:	Tian Ge, Martin Reuter, Anderson M. Winkler, Avram J. Holmes, Phil H. Lee, Lee S. Tirrell, Joshua L. Roffman, Randy L. Buckner, Jordan W. Smoller, Mert R. Sabuncu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms13291

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spelling	doaj-dcaa722e0e844e8ba5533697c41056352021-05-11T11:16:50ZengNature Publishing GroupNature Communications2041-17232016-11-017111010.1038/ncomms13291Multidimensional heritability analysis of neuroanatomical shapeTian Ge0Martin Reuter1Anderson M. Winkler2Avram J. Holmes3Phil H. Lee4Lee S. Tirrell5Joshua L. Roffman6Randy L. Buckner7Jordan W. Smoller8Mert R. Sabuncu9Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolCentre for Functional MRI of the Brain (FMRIB), University of OxfordAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolPsychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General HospitalAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical SchoolAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolPsychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General HospitalAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical SchoolNeuroanatomical shape measurements are multidimensional geometric descriptions of brain structure. This study develops multivariate heritability analysis methods and examines structural brain MRI scans and genetic data to estimate the heritability of neuroanatomical shape.https://doi.org/10.1038/ncomms13291
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Tian Ge Martin Reuter Anderson M. Winkler Avram J. Holmes Phil H. Lee Lee S. Tirrell Joshua L. Roffman Randy L. Buckner Jordan W. Smoller Mert R. Sabuncu
spellingShingle	Tian Ge Martin Reuter Anderson M. Winkler Avram J. Holmes Phil H. Lee Lee S. Tirrell Joshua L. Roffman Randy L. Buckner Jordan W. Smoller Mert R. Sabuncu Multidimensional heritability analysis of neuroanatomical shape Nature Communications
author_facet	Tian Ge Martin Reuter Anderson M. Winkler Avram J. Holmes Phil H. Lee Lee S. Tirrell Joshua L. Roffman Randy L. Buckner Jordan W. Smoller Mert R. Sabuncu
author_sort	Tian Ge
title	Multidimensional heritability analysis of neuroanatomical shape
title_short	Multidimensional heritability analysis of neuroanatomical shape
title_full	Multidimensional heritability analysis of neuroanatomical shape
title_fullStr	Multidimensional heritability analysis of neuroanatomical shape
title_full_unstemmed	Multidimensional heritability analysis of neuroanatomical shape
title_sort	multidimensional heritability analysis of neuroanatomical shape
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-11-01
description	Neuroanatomical shape measurements are multidimensional geometric descriptions of brain structure. This study develops multivariate heritability analysis methods and examines structural brain MRI scans and genetic data to estimate the heritability of neuroanatomical shape.
url	https://doi.org/10.1038/ncomms13291
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Multidimensional heritability analysis of neuroanatomical shape

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