β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio

β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio

<p>Abstract</p> <p>Background</p> <p>β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. Employing a comprehensive methodological approach, the aim of our <it>in vitro </it>study was to elucidate nov...

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Bibliographic Details
Main Authors: Koritke Petra, Rink Lothar, Hennig Holger, Brand Joerg M, Frohn Christoph, Hensel Jenny, Langenkamp Ulrich, Luhm Juergen, Wittkopf Nadine, Williams David L, Mueller Antje
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/7/5

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