Identification and correction of systematic error in high-throughput sequence data

<p>Abstract</p> <p>Background</p> <p>A feature common to all DNA sequencing technologies is the presence of base-call errors in the sequenced reads. The implications of such errors are application specific, ranging from minor informatics nuisances to major problems affe...

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Bibliographic Details
Main Authors: Meacham Frazer, Boffelli Dario, Dhahbi Joseph, Martin David IK, Singer Meromit, Pachter Lior
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/451