A likelihood approach to testing hypotheses on the co-evolution of epigenome and genome.

Central questions to epigenome evolution include whether interspecies changes of histone modifications are independent of evolutionary changes of DNA, and if there is dependence whether they depend on any specific types of DNA sequence changes. Here, we present a likelihood approach for testing hypo...

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Bibliographic Details
Main Authors: Jia Lu, Xiaoyi Cao, Sheng Zhong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006673