Ionic mechanism underlying optimal stimuli for neuronal excitation: role of Na+ channel inactivation.
The ionic mechanism underlying optimal stimulus shapes that induce a neuron to fire an action potential, or spike, is relevant to understanding optimal information transmission and therapeutic stimulation in the nervous system. Here we analyze for the first time the ionic basis for stimulus optimali...
Main Authors: | John R Clay, Daniel B Forger, David Paydarfar |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3458826?pdf=render |
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