EWS/FLI1 target genes and therapeutic opportunities in Ewing sarcoma
Ewing sarcoma family of tumors are aggressive bone malignancies that affect children and young adults. Ewing sarcoma is the second most common primary bone malignancy in pediatric patients. Although significant progress has been made in the treatment of Ewing sarcoma since it was first described in...
Main Authors: | Florencia eCidre, Javier eAlonso |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-07-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00162/full |
Similar Items
-
SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth
by: Siyuan Su, et al.
Published: (2021-07-01) -
ACETYLATION INCREASES EWS-FLI1 DNA BINDING AND TRANSCRIPTIONAL ACTIVITY
by: Silke eSchlottmann, et al.
Published: (2012-09-01) -
Characterization of length-dependent GGAA-microsatellites in EWS/FLI mediated Ewing sarcoma oncogenesis
by: Johnson, Kirsten M.
Published: (2018) -
Ewing Sarcoma
by: Hee Young Ju
Published: (2019-04-01) -
Salient Features of Mesenchymal Stem Cells – Implications for Ewing Sarcoma Modeling
by: Michael James Monument, et al.
Published: (2013-02-01)