Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates.

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates.

Cholinergic, muscarinic receptor agonists exhibit functional dopamine antagonism and muscarinic receptors have been suggested as possible future targets for the treatment of schizophrenia and drug abuse. The muscarinic ligand (5R,6R)-6-(3-butylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane (B...

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Bibliographic Details
Main Authors: Maibritt B Andersen, Carrie Hughes Croy, Ditte Dencker, Thomas Werge, Frank P Bymaster, Christian C Felder, Anders Fink-Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4399838?pdf=render

Internet

http://europepmc.org/articles/PMC4399838?pdf=render

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