Rapamycin Attenuates Pulmonary Allergic Vasculitis in Murine Model by Reducing TGF-βProduction in the Lung

Rapamycin Attenuates Pulmonary Allergic Vasculitis in Murine Model by Reducing TGF-βProduction in the Lung

Background: : Rapamycin has been reported to inhibit mesenchymal cell proliferation in a murine model of pulmonary fibrosis. In the present study, we examined the effects of rapamycin on vascular remodeling including intraluminal myofibroblast proliferation in a murine model of allergic vasculitis w...

Full description

Bibliographic Details
Main Authors: Rumi Koizumi, Nobuhito Sasaki, Yutaka Nakamura, Naomi Suzuki, Takashi Sawai, Kohei Yamauchi
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Allergology International
Subjects:
allergic vasculitis
C57BL/6
murine model
rapamycin
TGF-β
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015300538

Similar Items

Similar Items