SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF

SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF

The prognosis of breast cancer brain metastasis (BCBM) is extremely poor due to its resistance to conventional therapy. Elucidation of the molecular mechanisms of BCBM could contribute to the development of new therapeutic targets. In this study, we isolated RNA samples from primary breast cancer or...

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Bibliographic Details
Main Authors: Weikai Xiao, Shaoquan Zheng, Xinhua Xie, Xing Li, Lijuan Zhang, Anli Yang, Jian Wang, Hailin Tang, Xiaoming Xie
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
breast cancer
brain metastasis
SOX2
FSCN1
HBEGF
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030022X

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