Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein

Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein

The majority of mitochondrial proteins are targeted to mitochondria by N-terminal presequences and use the TIM23 complex for their translocation across the mitochondrial inner membrane. During import, translocation through the channel in the inner membrane is coupled to the ATP-dependent action of a...

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Bibliographic Details
Main Authors: Rupa Banerjee, Christina Gladkova, Koyeli Mapa, Gregor Witte, Dejana Mokranjac
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
TIM23
mitochondria
protein translocation/sorting
Hsp70
Online Access:https://elifesciences.org/articles/11897

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