Embelin Prevents Seizure and Associated Cognitive Impairments in a Pentylenetetrazole-Induced Kindling Zebrafish Model

Embelin Prevents Seizure and Associated Cognitive Impairments in a Pentylenetetrazole-Induced Kindling Zebrafish Model

Epilepsy is a neuronal disorder associated with several neurological and behavioral alterations characterized by recurrent spontaneous epileptic seizures. Despite having more than 20 anti-epileptic drugs (AEDs), they only provide a symptomatic treatment. As well as, currently available AEDs also dis...

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Bibliographic Details
Main Authors: Uday Praful Kundap, Yam Nath Paudel, Yatinesh Kumari, Iekshan Othman, Mohd. Farooq Shaikh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
chronic epilepsy
zebrafish
three-axis maze
cognition
behavior
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00315/full

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