Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats

Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats

A peptic ulcer is an alimentary tract injury that leads to a mucosal defect reaching the submucosa. This work aimed to optimize and maximize ellagic acid (EA) loading in Ca pectinate floating beads to maximize the release for 24 h. Three factors were selected: Ca pectinate concentration (X1, 1–3 w/v...

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Bibliographic Details
Main Authors: Nabil A. Alhakamy, Shaimaa M. Badr-Eldin, Osama A. A. Ahmed, Abdulrahman A. Halwani, Hibah M. Aldawsari, Mohamed A. El-Moselhy, Aliaa Anter, Sara S. Sharkawi, Muhammad H. Sultan, Osama A. A. Madkhali, Muhammed A. Bakhrebah, Mohammad N. Alomary, Wesam H. Abdulaal, Usama A. Fahmy
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
stomatitis
formulation
peptic ulcer
NSAIDs
factorial design
pharmacokinetics
Online Access:https://www.mdpi.com/2218-273X/10/7/1006

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https://www.mdpi.com/2218-273X/10/7/1006

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