Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils

Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils

Summary: Myeloid cells co-expressing the markers CD11b, Ly-6G, and SiglecF can be found in large numbers in murine lung adenocarcinomas and accelerate cancer growth by fostering tumor cell invasion, angiogenesis, and immunosuppression; however, some of these cells’ fundamental features remain unexpl...

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Bibliographic Details
Main Authors: Christina Pfirschke, Camilla Engblom, Jeremy Gungabeesoon, Yunkang Lin, Steffen Rickelt, Rapolas Zilionis, Marius Messemaker, Marie Siwicki, Genevieve M. Gerhard, Anna Kohl, Etienne Meylan, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Cell Reports
Subjects:
neutrophils
cancer
myeloid cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720311530

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