Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study

Background: The aim of the study is to investigate whether the circadian IOP rhythm can be influenced by combined cataract surgery with high frequency deep sclerotomy (HFDS) and whether intraocular pressure (IOP) can be significantly reduced by HFDS. Methods: In our study 10 patients were included,...

Full description

Bibliographic Details
Main Authors: Bojan Pajic, Mirko Resan, Brigitte Pajic-Eggspuehler, Horace Massa, Zeljka Cvejic
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/16/3472
id doaj-dc5bab4181e74ceb8e114e12bf4e7cc3
record_format Article
spelling doaj-dc5bab4181e74ceb8e114e12bf4e7cc32021-08-26T13:54:57ZengMDPI AGJournal of Clinical Medicine2077-03832021-08-01103472347210.3390/jcm10163472Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective StudyBojan Pajic0Mirko Resan1Brigitte Pajic-Eggspuehler2Horace Massa3Zeljka Cvejic4Eye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, SwitzerlandFaculty of Medicine of the Military Medical Academy, University of Defense, 11000 Belgrade, SerbiaEye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, SwitzerlandDepartment of Clinical Neurosciences, Division of Ophthalmology, Geneva University Hospitals, 1205 Geneva, SwitzerlandDepartment of Physics, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 4, 21000 Novi Sad, SerbiaBackground: The aim of the study is to investigate whether the circadian IOP rhythm can be influenced by combined cataract surgery with high frequency deep sclerotomy (HFDS) and whether intraocular pressure (IOP) can be significantly reduced by HFDS. Methods: In our study 10 patients were included, in whom 24 h IOP monitoring was installed before and after HFDS/cataract surgery using a Triggerfish. HFDS is a minimally invasive glaucoma surgery (MIGS). Results: After performed HFDS combined with cataract surgery, the IOP was reduced from 27.7 ± 2.11 mmHg to 14.4 ± 2.59 mmHg, which is highly significant (<i>p</i> < 0.001). The contact lens sensor (CLS) cosinor analysis pre- and postoperatively showed that the circadian rhythm is not influenced by the surgery, i.e., the circadian IOP rhythm did not show significant differences before and after surgery. Conclusions: HFDS combined with cataract surgery is a potent surgical method that can significantly reduce the IOP. However, the circadian rhythm cannot be changed by the surgery. The acrophase remained during the night in all patients.https://www.mdpi.com/2077-0383/10/16/3472TriggerfishIOP patternminimal invasive glaucoma surgery (MIGS)high frequency deep sclerotomy (HFDS)
collection DOAJ
language English
format Article
sources DOAJ
author Bojan Pajic
Mirko Resan
Brigitte Pajic-Eggspuehler
Horace Massa
Zeljka Cvejic
spellingShingle Bojan Pajic
Mirko Resan
Brigitte Pajic-Eggspuehler
Horace Massa
Zeljka Cvejic
Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
Journal of Clinical Medicine
Triggerfish
IOP pattern
minimal invasive glaucoma surgery (MIGS)
high frequency deep sclerotomy (HFDS)
author_facet Bojan Pajic
Mirko Resan
Brigitte Pajic-Eggspuehler
Horace Massa
Zeljka Cvejic
author_sort Bojan Pajic
title Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
title_short Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
title_full Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
title_fullStr Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
title_full_unstemmed Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study
title_sort triggerfish recording of iop patterns in combined hfds minimally invasive glaucoma and cataract surgery: a prospective study
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2021-08-01
description Background: The aim of the study is to investigate whether the circadian IOP rhythm can be influenced by combined cataract surgery with high frequency deep sclerotomy (HFDS) and whether intraocular pressure (IOP) can be significantly reduced by HFDS. Methods: In our study 10 patients were included, in whom 24 h IOP monitoring was installed before and after HFDS/cataract surgery using a Triggerfish. HFDS is a minimally invasive glaucoma surgery (MIGS). Results: After performed HFDS combined with cataract surgery, the IOP was reduced from 27.7 ± 2.11 mmHg to 14.4 ± 2.59 mmHg, which is highly significant (<i>p</i> < 0.001). The contact lens sensor (CLS) cosinor analysis pre- and postoperatively showed that the circadian rhythm is not influenced by the surgery, i.e., the circadian IOP rhythm did not show significant differences before and after surgery. Conclusions: HFDS combined with cataract surgery is a potent surgical method that can significantly reduce the IOP. However, the circadian rhythm cannot be changed by the surgery. The acrophase remained during the night in all patients.
topic Triggerfish
IOP pattern
minimal invasive glaucoma surgery (MIGS)
high frequency deep sclerotomy (HFDS)
url https://www.mdpi.com/2077-0383/10/16/3472
work_keys_str_mv AT bojanpajic triggerfishrecordingofioppatternsincombinedhfdsminimallyinvasiveglaucomaandcataractsurgeryaprospectivestudy
AT mirkoresan triggerfishrecordingofioppatternsincombinedhfdsminimallyinvasiveglaucomaandcataractsurgeryaprospectivestudy
AT brigittepajiceggspuehler triggerfishrecordingofioppatternsincombinedhfdsminimallyinvasiveglaucomaandcataractsurgeryaprospectivestudy
AT horacemassa triggerfishrecordingofioppatternsincombinedhfdsminimallyinvasiveglaucomaandcataractsurgeryaprospectivestudy
AT zeljkacvejic triggerfishrecordingofioppatternsincombinedhfdsminimallyinvasiveglaucomaandcataractsurgeryaprospectivestudy
_version_ 1721192426156064768