ELEVATION OF SERUM C-REACTIVE PROTEIN AND S100 PROTEINS FOR SYSTEMIC INFLAMMATION IN AUTISTIC CHILDREN
The pathogenesis of autism, a neurological disorder severely affecting young children, may involve inflammation and autoimmunity. In this report, the distribution of acute-phase C-reactive protein (CRP) and S100 proteins was examined in normal and autistic children. Their serum levels were measured...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Philosophy, Institute of Special Education and Rehabilitation
2005-12-01
|
| Series: | Journal of Special Education and Rehabilitation |
| Subjects: | |
| Online Access: | http://jser.fzf.ukim.edu.mk/pdf/3-42005/13-SING%20VIENGRA-Iskustva%20i%20novini%20od%20svetot.pdf |
| Summary: | The pathogenesis of autism, a neurological disorder severely affecting young children, may involve inflammation and autoimmunity. In this report, the distribution of acute-phase C-reactive protein (CRP) and S100 proteins was examined in normal and autistic children. Their serum levels were measured by enzyme-linked immunosorbent assay (ELISA). Autistic children were found to have significantly higher than normal levels of CRP (p=0.005) and S100 proteins (p=0.03). The existence of elevated levels of CRP and S100 proteins in autistic children is an excellent sign of systemic inflammation that may contribute to the neuropathology of this brain disorder. |
|---|---|
| ISSN: | 1409-6099 1857-663X |