CLIP-related methodologies and their application to retrovirology

Abstract Virtually every step of HIV-1 replication and numerous cellular antiviral defense mechanisms are regulated by the binding of a viral or cellular RNA-binding protein (RBP) to distinct sequence or structural elements on HIV-1 RNAs. Until recently, these protein–RNA interactions were studied l...

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Bibliographic Details
Main Authors: Paul D. Bieniasz, Sebla B. Kutluay
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Retrovirology
Online Access:http://link.springer.com/article/10.1186/s12977-018-0417-2