Histone Deacetylase Inhibitors Enhance Cell Killing and Block Interferon-Beta Synthesis Elicited by Infection with an Oncolytic Parainfluenza Virus

Previous results have shown that infection with the cytoplasmic-replicating parainfluenza virus 5 mutant P/V-CPI- sensitizes cells to DNA damaging agents, resulting in the enhanced killing of airway cancer cells. Here, we have tested the hypothesis that histone deacetylase (HDAC) inhibitors can also...

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Bibliographic Details
Main Authors: Candace R. Fox, Griffith D. Parks
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/5/431