ГЕПАТОПРОТЕКТОРНЫЕ ЭФФЕКТЫ ПРЕПАРАТА МЕКСИКОР ® ПРИ ЛЕЧЕНИИ БОЛЬНЫХ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮ И САХАРНЫМ ДИАБЕТОМ 2 ТИПА
The prospective, randomized, open-label 16-week trial studied Mexicor ® (part of complex treatment) effects in patients with chronic heart failure and type 2 diabetes mellitus, on structural and functional parameters of the liver. Hepatoprotecive facilities of Mexicor ® were demonstrated: a signific...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
SINAPS LLC
2013-06-01
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| Series: | Arhivʺ Vnutrennej Mediciny |
| Subjects: | |
| Online Access: | https://www.medarhive.ru/jour/article/view/196 |
| Summary: | The prospective, randomized, open-label 16-week trial studied Mexicor ® (part of complex treatment) effects in patients with chronic heart failure and type 2 diabetes mellitus, on structural and functional parameters of the liver. Hepatoprotecive facilities of Mexicor ® were demonstrated: a significant decrease in the severity of cytolysis, cholestasis, steatosis index, the ability to reduce severity of structural changes in the liver by ultrasound. These hepatoprotective effects are realized by Mexicor ® influencing on lipid peroxidation, activity of antioxidant enzymes, decreasing of chronic systemic inflammation expressions. The use of Mexicor ® promotes more evident associated hypoglycemic effect and reduces the severity of insulin resistance. Marked hepatoprotective effects of Mexicor ® improves not only metabolic processes in the liver, but also can significantly change the cardiovascular risk in these patients. |
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| ISSN: | 2226-6704 2411-6564 |