DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

Abstract Background DL-3-n-butylphthalide (NBP) was demonstrated to increase the cerebral blood flow (CBF) in the animal models, but there are no clinic studies to verify this. We aimed to explore the effect of NBP on improving cerebral hypoperfusion caused by cerebral large-vessel stenosis. Methods...

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Bibliographic Details
Main Authors: Dawei Chen, Yanwei Yin, Jin Shi, Fen Yang, Kehua Wang, Faguo Zhao, Wenping Li, Bin Li
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Neurology
Subjects:
DL-3-n-butylphthalide
Cerebral atherosclerotic stenosis
Cerebral hypoperfusion
Cerebral blood flow
Single-photon emission computed tomography
Online Access:http://link.springer.com/article/10.1186/s12883-020-01801-5

Internet

http://link.springer.com/article/10.1186/s12883-020-01801-5

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