SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden

<p>Abstract</p> <p>Native Factor V is an anticoagulant, but when activated by thrombin, Factor X or platelet proteases, it becomes a procoagulant. Due to these double properties, Factor V plays a crucial role in the regulation of coagulation/anticoagulation balance.</p> <p...

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Bibliographic Details
Main Authors: Ferrazzi Paola, Quaglia Ilaria, Rota Lidia, Lepretti Marilena, Di Micco Biagio, Di Micco Gianluca, Di Micco Pierpaolo
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/69