Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance

Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance

Abstract Background Chemotherapy is a widely used treatment for cancer. However, the development of acquired multidrug resistance (MDR) is a serious issue. Emerging evidence has shown that the extracellular vesicles (EVs) mediate MDR, but the underlying mechanism remains unclear, especially the effe...

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Bibliographic Details
Main Authors: Xiaokun Wang, Dongjuan Qiao, Likun Chen, Meng Xu, Shupeng Chen, Liyan Huang, Fang Wang, Zhen Chen, Jiye Cai, Liwu Fu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Cancer
Subjects:
Extracellular vesicles
Intercellular transfer
Multidrug resistance
ABCB1
Chemotherapeutic drugs
Online Access:https://doi.org/10.1186/s12943-019-1114-z

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