Modification of the protein’s composition from the neurospecifical intermediate filaments in different parts of the red’s brain depend on actions of the ionisition radiation

• Main Author: Romanenko L.A.
• Format: Article
• Language: Russian
• Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2008-01-01
• Series: Морфологія
• Subjects: neurofilaments; ionisition radiation; cytoskeleton
• Online Access: http://www.morphology.dp.ua/_pub/MORPHO-2008-02-01/08rlanro.pdf

In our work was spend the research about modification of the protein’s composition from the neurospecifical intermediate filaments in different parts of the red’s brain, which depend on duration actions of the ionisition radiation. To the research traded on 30 reds. It were devided on groups, which depend on fate of radiation – 1 day, 1,2 and 3 week, like the control group. We spending the Rh – irradiation on the putting RUM – 17 in the fate 0,00129 Kl/kg. We was devide the brain on parts ( there are: the cortex, the cerebellum, the gypocamp), homogenize, centrifugize. Nhe quantity of neurofilaments (NF) was defined by the rocket-lineal immunoelectrophoresis. We defined reliable changes of the neurofilaments’s support in aii groups, which was expose by the action of small – fate ionisition radiation. The character of manifestations from this changes determined by the fate of action. So, the support of the protein NF at the experimental reds was not practically differ of control group by the unitary irradiation. The extension of the quantity of neurofilaments was set in the cortex of greater hemispheres, the cerebellum, the gypocamp at the irradiation reds during 21 days. We colligated this changes with polypep-tide 210 kDa.