Critical Components for Spontaneous Activity and Rhythm Generation in Spinal Cord Circuits in Culture

Critical Components for Spontaneous Activity and Rhythm Generation in Spinal Cord Circuits in Culture

Neuronal excitability contributes to rhythm generation in central pattern generating networks (CPGs). In spinal cord CPGs, such intrinsic excitability partly relies on persistent sodium currents (INaP), whereas respiratory CPGs additionally depend on calcium-activated cation currents (ICAN). Here, w...

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Bibliographic Details
Main Authors: Samuel Buntschu, Anne Tscherter, Martina Heidemann, Jürg Streit
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
rhythm generation
intrinsic spiking
TRP channels
multielectrode arrays
central pattern generator
ICAN
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00081/full

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