Systematic quantitative analysis of H2A and H2B variants by targeted proteomics

Systematic quantitative analysis of H2A and H2B variants by targeted proteomics

Abstract Background Histones organize DNA into chromatin through a variety of processes. Among them, a vast diversity of histone variants can be incorporated into chromatin and finely modulate its organization and functionality. Classically, the study of histone variants has largely relied on antibo...

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Bibliographic Details
Main Authors: Sara El Kennani, Annie Adrait, Olga Permiakova, Anne-Marie Hesse, Côme Ialy-Radio, Myriam Ferro, Virginie Brun, Julie Cocquet, Jérôme Govin, Delphine Pflieger
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Epigenetics & Chromatin
Subjects:
Histone variants
Chromatin
Proteomics
Targeted proteomics
SRM
PRM
Online Access:http://link.springer.com/article/10.1186/s13072-017-0172-y

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