Insulin-like Growth Factor 1 gene polymorphism and breast cancer risk

Insulin-like Growth Factor 1 gene polymorphism and breast cancer risk

ABSTRACT Insulin-like Growth Factor-1 (IGF-1) gene polymorphism has been associated with an increased risk for breast cancer. IGF-1 is a key regulator of proliferation, cell differentiation and apoptosis. It has important mitogenic and anti-apoptotic activities in normal cells and in breast cancer c...

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Bibliographic Details
Main Authors: DANYLO R. COSTA-SILVA, MARIA DA CONCEIÇÃO BARROS-OLIVEIRA, RAFAEL S. BORGES, CLÉCITON B. TAVARES, UMBELINA S. BORGES, FRANCISCO A. ALVES-RIBEIRO, VLADIMIR C. SILVA, BENEDITO B. DA SILVA
Format: Article
Language:English
Published: Academia Brasileira de Ciências
Series:Anais da Academia Brasileira de Ciências
Subjects:
Breast cancer
risk factors
IGF-1
IGF-1 gene polymorphism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016005020107&lng=en&tlng=en

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