Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyomavirus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppresed patients and rarely associated with systemic lupus erythematosus. I...

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Bibliographic Details
Main Authors: Fabrício Guimarães Gonçalves, Leslie Lamb, Raquel Del Carpio-O'Donovan
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
PML
leukoencephalopathy
progressive multifocal posterior fossa
magnetic resonance
spectroscopy
diffusion weighted images
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600020&lng=en&tlng=en
Description
Summary:Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyomavirus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppresed patients and rarely associated with systemic lupus erythematosus. In the central nervous system PML demyelinating lesions occur in the supratentorial compartment. The authors describe a rare case of PML secondary to SLE treatment with atypical presentation restricted to the posterior fossa.
ISSN:1678-4391

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