Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

<p>Abstract</p> <p>Background</p> <p>The multi-arm multi-stage (MAMS) trial is a new paradigm for conducting randomised controlled trials that allows the simultaneous assessment of a number of research treatments against a single control arm. MAMS trials provide earlier...

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Bibliographic Details
Main Authors: Dearnaley David P, Clarke Noel W, James Nicholas D, Parmar Mahesh KB, Sydes Matthew R, Mason Malcolm D, Morgan Rachel C, Sanders Karen, Royston Patrick
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/10/1/39

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