Renal transplant patient survives a donor-derived abdominal invasive mucormycosis (Lichtheimia ramosa)

Mucormycosis is a life-threatening invasive fungal infection, most commonly described in severely immunocompromised patients. It is characterized by rapid invasive growth of the fungus and often with fatal outcome. We report a case of a renal transplant recipient diagnosed with a donor-derived invas...

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Bibliographic Details
Main Authors: E.M. Spithoven, A.H.W. Bruns, B.J. Petri, P.J. Haas, T.Q. Nguyen, F. Hagen, A.D. van Zuilen
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Medical Mycology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211753920300580
Description
Summary:Mucormycosis is a life-threatening invasive fungal infection, most commonly described in severely immunocompromised patients. It is characterized by rapid invasive growth of the fungus and often with fatal outcome. We report a case of a renal transplant recipient diagnosed with a donor-derived invasive mucormycosis. In this patient, we used a step-wise approach of withdrawal of immunosuppressants, antifungal induction therapy, extensive surgical debridement of all (potentially) infected tissue, abdominal irrigation of liposomal amphotericin B and interferon gamma. Due to rapid diagnosis and intensive therapy the patient survived.
ISSN:2211-7539