TILLING is an effective reverse genetics technique for <it>Caenorhabditis elegans</it>
<p>Abstract</p> <p>Background</p> <p>TILLING (Targeting Induced Local Lesions in Genomes) is a reverse genetic technique based on the use of a mismatch-specific enzyme that identifies mutations in a target gene through heteroduplex analysis. We tested this technique in...
Main Authors: | Zetka Monique C, Rose Ann M, O'Neil Nigel J, Gilchrist Erin J, Haughn George W |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-10-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/7/262 |
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