Impact of Halogen Substituents on Interactions between 2-Phenyl-2,3-dihydroqulinazolin-4(1H)-one Derivatives and Human Serum Albumin

A novel type of 2-(un)substituted phenyl-2,3-dihydroquinazolin-4(1H)-one (DQL) derivatives were designed and synthesized to study the impact of halogen substituents on interactions between DQL and human serum albumin (HSA) by comparison methodology. The interactions between DQL and HSA were studied...

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Bibliographic Details
Main Authors: Shangzhong Liu, Min Wang, Junjun Ou, Lei Wang, Cong Lv, Yi Wang, Feng Liu
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Molecules
Subjects:
DQL
Online Access:http://www.mdpi.com/1420-3049/17/2/2000/